Penta-erythritol Tetranitrate in Treatment of Angina

A clinical trial of penta-erythritol tetranitrate, a khellin derivative (recordil), and iproniazid in angina of effort.

That there is room for improvement in the medicinal treatment of angina of effort, no one will dispute. The clinical trial to be described was designed to test the efficacy of a khellin derivative, iproniazid, and the already widely used penta-erythritol tetranitrate, in the relief of anginal pain. THE DRUGS Penta-erythritol tetranitrate (P.E.T.N.) has the chemical formula CH20NO2 CH2ONO2 C CH2...

Effects of erythrol tetranitrate and amotriphene on exercise tolerance tests in angina pectoris.

OBJECTIVE EVIDENCES for angina pectoris, in the absence of proved myocardial infarction or grossly abnormal electrocardiograms, are more or less limited to abnormal electrocardiographic changes induced by exercise or hypoxemia. Similarly, while termination or prevention of angina is notoriously unreliable in the evaluation of "coronary dilator" drugs, their effects on provoked abnormalities in ...

The prolonged effect of pentaerythritol tetranitrate on exercise capacity in stable effort angina pectoris.

We studied the effect of a single oral dose of 40 mg of pentaerythritol tetranitrate (PETN) on the exercise capacity of ten patients with angina pectoris. The study design was a randomized double-blind crossover comparing the effects of 40 mg of oral PETN with placebo on exercise tolerance. Patients were exercised to moderate angina pectoris before and 2 1/2 and 4 1/2 hours after receiving the ...

Metabolism of Inorganic Nitrite and Nitrate Esters Ii. the Enzymatic Reduction of Nitroglycerin and Erythritol Tetranitrate by Glutathione

modern surgical techniques in treatment of patients with cleft lip & cleft palate

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